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Strychnine




Strychnine

Strychnine is a toxic alkaloid derived from the seeds of the trees Strychnos nux vomica, Strychnos ignatii (S. sancta Ingnatius), and Strychnos tiente (Upas tree), that can be found in India, southern Asia, northern Australia, and Hawaii.

Strychnine is an alkaloid that is found in Strychnos nux-vomica (Loganiaceae). It causes excitation of all parts of the central nervous system, with a characteristic motor pattern. Strychnine is a competitive antagonist at inhibitory neurotransmitter glycine receptors .

Strychnine is a glycine receptor antagonist not associated with the N-methyl-D-aspartate (NMDA) receptor. It is an alkaloid extracted from Strychnos nux vomica seeds. Strychnine is a colorless, odourless and bitter tasting powder. It is absorbed in skin, gastrointestinaland respiratory tract.

Warning: Strychnine sulfate may induce convulsions within 15 to 60 minutes following exposure. Caution is advised. Vital signs should be monitored closely. Signs and Symptoms of Acute Strychnine Sulfate Exposure: Signs and symptoms of acute exposure to strychnine sulfate generally involve excitation of all portions of the central nervous system.

Clinical description. The major identifying clinical features of strychnine poisoning through ingestion are severe, painful spasms of the neck, back, and limbs and convulsions with an intact sensorium. Signs and symptoms might progress to coma. Tachycardia and hypertension are .


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3 Replies to "Strychnine"

  1.  · What strychnine is. Strychnine is a white, odorless, bitter crystalline powder that can be taken by mouth, inhaled (breathed in), or mixed in a solution and given intravenously (injected directly into a vein). Strychnine is a strong poison; only a small amount is needed to .

  2. Strychnine is a monoterpenoid indole alkaloid that is strychnidine bearing a keto substituent at the position. It has a role as an avicide, a glycine receptor antagonist, a cholinergic antagonist, a rodenticide and a neurotransmitter agent. It is a monoterpenoid indole Molecular Formula: C21H22N2O2.

  3. Strychnine is a lethal natural substance that is used for the control of rodents and wild animals. Because strychnine is highly toxic and can be rapidly absorbed through the mucous membranes of the mouth, stomach, and small intestines. Most products containing Strychnine are restricted use rodenticides which only certified pest control.

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